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[Paper] Optimizing Plasma Formation and Minimizing Microcavitation to Enhance Clinical Outcomes in Keratorefractive Lenticule Extraction

2025.08.01 2016

EYEREUM Eye Clinic’s new research paper has been officially published in the July 2025  issue of the Journal of Refractive Surgery. 

Journal of Refractive Surgery Vol.41, No.7 

Optimizing Plasma Formation and Minimizing Microcavitation to Enhance Clinical Outcomes in Keratorefractive Lenticule Extraction

https://journals.healio.com/doi/10.3928/1081597X-20250509-05


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Home → Journal of Refractive Surgery → Vol. 41, No. 7

RESEARCH ARTICLE

Optimizing Plasma Formation and Minimizing Microcavitation to Enhance Clinical Outcomes in Keratorefractive Lenticule Extraction

Soyoung Ryu, MD, David S. Y. Kang, MD, Kang Yoon Kim, MD, Samuel Arba-Mosquera, PhD, Byunghoon Chung, MD, Ikhyun Jun, MD, PhD, Ahmed Elsheikh, PhD, Kyoung Yul Seo, MD, PhD, and Tae-im Kim, MD, PhD

Journal
Journal of Refractive Surgery, 2025;41(7):e635-e644
Published Online
July 01, 2025
DOI
https://doi.org/10.3928/1081597X-20250509-05

Abstract

PURPOSE To compare early postoperative visual outcomes and higher order aberrations (HOAs) between plasma and conventional keratorefractive lenticular extractions (P-KLEx and C-KLEx).

METHODS In this retrospective case series, records of patients who underwent KLEx surgery using two protocols—C-KLEx (symmetric spot/track distance laser spacing, 100-nJ pulse energy, VisuMax 500; Carl Zeiss Meditec) or P-KLEx (asymmetric spot/track distance laser spacing, 85-nJ pulse energy, VisuMax 800; Carl Zeiss Meditec)—were reviewed. Both groups received an identical total energy dosage of 625 mJ/cm². Postoperative visual acuity and corneal higher order aberrations (HOAs) were analyzed at 1 day, 2 weeks, and 2 months.

Purpose : To compare early postoperative visual outcomes and higher order aberrations (HOAs) between plasma and conventional keratorefractive lenticular extractions (P-KLEx(Plasma SMILE) and C-KLEx).

Conclusions : P-KLEx, which minimizes microcavitation and creates a lenticule with near-pure plasma, shows more favorable outcomes than C-KLEx, yielding better early postoperative visual acuities and reduced induction of corneal HOAs.


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