공지사항 - 아이리움의 새로운 소식을 확인해 보세요.

[소식] 중국 상하이 굴절교정심포지엄, 각막콜라겐교차결합술 강연

2018.01.11 11388

지난 1월 6일, 아이리움안과 강성용 원장이 중국 상하이 굴절교정심포지엄에서

<원추각막 치료와 레이저 굴절교정술 부작용 예방을 위한 각막콜라겐교차결합술(CXL)>에 대한

초청 강연을 진행했습니다. 

CONCLUSIONS

  • 1. Combined tPRK and Prophylactic Accelerated CXL Demonstrated Comparable Predictability, Efficacy, and Safety Compared with tPRK Alone.
  • 2. Combined tPRK and CXL Provides Better UDVA in the Early Postop. Period.
  • 3. Better Refractive Outcomes at 12 months Postoperatively in Terms of Spherical Error and MRSE.

EYE REUM OPHTHALMIC CLINIC


Figure corre bIOP amp phot

이번 강연은 중국에 처음으로 KXL시스템으로 CXL을 시행한

 푸단대학교의 쩌우씽타오 교수의 초청으로 진행됐습니다.


강성용 원장은 아시아 유일의 아베드로 의학자문위원 자격으로 초청되었습니다.

강성용 원장은 아시아-태평양 의학자문을 맡고 있습니다.


강성용 원장의 강연을 듣기 위해 이날 500명의 중국의사가 한 자리에 모였는데요. 
BMC, JCRS 등 SCI 학술지에 등재된 논문 내용을 바탕으로

각막콜라겐교차결합술의 우수한 임상증례와 효과를 소개했습니다.


Table 5 Preoperative and postoperative corneal biomechanical properties in eyes undergoing combined corneal wavefront-guided transepithelial photorefractive keratectomy and accelerated corneal collagen cross-linking after intracorneal ring segment implantation in patients with moderate keratoconus

ParameterPreop (Baseline, before ICRS)Before tPRK-CXLP*1 mon after tPRK-CXL3 mon after tPRK-CXLP*6 mon after tPRK-CXLP*P†P‡P§
Radius (mm)5.33 ± 0.95 (3.56 to 8.05)4.89 ± 0.71 (3.89 to 6.52).0424.34 ± 0.54 (2.98 to 5.10)4.51 ± 0.65 (3.00 to 5.60).0934.70 ± 0.67 (3.19 to 5.85)<.001.023.012.919
DA (mm)1.09 ± 0.13 (0.89 to 1.43)1.07 ± 0.11 (0.88 to 1.36).9381.08 ± 0.11 (0.91 to 1.39)1.03 ± 0.11 (0.91 to 1.35).0141.01 ± 0.11 (0.86 to 1.36).008.044.012.042
MCF (1/mm)0.19 ± 0.03 (0.12 to 0.28)0.21 ± 0.03 (0.15 to 0.26).0470.23 ± 0.03 (0.20 to 0.34)0.23 ± 0.04 (0.18 to 0.33).3710.21 ± 0.03 (0.17 to 0.32)<.001.034.005.919

Analysis Summary

  • Deformation Amplitude Decreased - Strengthening Despite Tissue Removal?
  • Radius (mm) Decreased -> Weakening?

-'중증 원추각막 환자에게 링 삽입술+코웨이브+콜라겐교차결합술'을 시행한 뒤 시력이 재활된 사례-

(2017 BMC 논문 中)

EYEREUM OPHTHALMIC CLINIC

RESEARCH ARTICLE: BMC Ophthalmology

Lee et al. BMC Ophthalmology (2017) 17:270 DOI 10.1186/s12886-017-0656-1

Visual rehabilitation in moderate keratoconus: combined corneal wavefront-guided transepithelial photorefractive keratectomy and high-fluence accelerated corneal collagen cross-linking after intracorneal ring segment implantation

Hun Lee, David Sung Yong Kang, Byoung Jin Ha, Jin Young Choi, Eung Kweon Kim, Kyoung Yul Seo and Tae-im Kim

Abstract

  • Background: To investigate the effects of combined corneal wavefront-guided transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) after intracorneal ring segment (ICRS) implantation in patients with moderate keratoconus.
  • Methods: Medical records of 23 eyes of 23 patients undergoing combined tPRK and CXL after ICRS implantation were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent (MRSE), corneal indices based on Scheimpflug tomography, higher-order aberrations (HOAs), and corneal biomechanical properties were evaluated before and after ICRS implantation, and at 1, 3, and 6 months after combined tPRK and CXL.
  • Results: There were significant improvements in final logMAR UDVA and logMAR CDVA, and reductions in sphere, MRSE, and all corneal indices from baseline. Significant improvements in logMAR UDVA and reductions in sphere, MRSE, maximal keratometry, keratometry at the apex, mean keratometry, and keratoconus index were noted after ICRS implantation. After tPRK and CXL, significant improvements in logMAR UDVA and logMAR CDVA, and reductions in cylinder and all corneal indices were observed. There were significant improvements in final root mean square HOAs and coma aberrations from baseline, but no changes from baseline after ICRS implantation. Significant reductions in final radius and deformation amplitude from baseline were noted.
  • Conclusions: Combined tPRK and accelerated CXL after ICRS implantation in moderate keratoconus appears to be a safe and effective treatment, providing an improvement in visual acuity, corneal indices, and HOAs.
  • Trial registration: retrospectively registered (identification no. NCT03355430). Date registered: 28/11/2017.
  • Keywords: Combined corneal wavefront-guided transepithelial photorefractive keratectomy and accelerated corneal collagen cross-linking, Intracorneal ring segment implantation, Keratoconus

Treatment Parameters

  • 365 nm UV
  • KXL, Avedro Inc (USA)
  • 15mw/cm2
  • 5.4J/ cm2
  • 1:1 Pulsatile Irradiation


EYEREUM OPHTHALMIC CLINIC

StagePre Ops/p ICRSs/p CWFG T PRK
Curvature/ tangential map (OD)Topography map showing corneal curvature before operation.Topography map showing corneal curvature status post Intracorneal Ring Segments.Topography map showing corneal curvature status post Corneal Wavefront-Guided Transepithelial Photorefractive Keratectomy.
Elevation map (OD)Elevation map before operation.Elevation map status post Intracorneal Ring Segments.Elevation map status post Corneal Wavefront-Guided Transepithelial Photorefractive Keratectomy.

Map Details

  • OD: Oculus Dexter (Right Eye)
  • a: Pre-operative tangential map
  • b: s/p ICRS tangential map
  • d: s/p CWFG T PRK tangential map

-올레이저 라섹과 콜라겐교차결합술이 결합된 라섹 엑스트라의 각막강성도 보존효과-

(2017 JRCS 논문 / 2017 CONEA 논문)

EYEREUM OPHTHALMIC CLINIC

JCRS Journal of Cataract & Refractive Surgery®

July 2017 Volume 43 Issue 7

Featured Articles

  • Effect of fine motor skills on surgical simulator performance
  • Rate of retinal tear and detachment after Nd:YAG capsulotomy
  • Cyclotorsion during femtosecond laser-assisted cataract surgery
  • Schlemm canal scaffold microstent with cataract surgery: Two-year multicenter

Effect of accelerated corneal crosslinking combined with transepithelial photorefractive keratectomy on dynamic corneal response parameters and biomechanically corrected intraocular pressure measured with a dynamic Scheimpflug analyzer in healthy myopic patients

Hun Lee, MD, Cynthia J. Roberts, PhD, Renato Ambrósio Jr., MD, PhD, Ahmed Elsheikh, PhD, David Sung Yong Kang, MD, Tae-im Kim, MD, PhD

From the Department of Ophthalmology (Lee), International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, the Institute of Vision Research (Lee, Kim), Department of Ophthalmology, Yonsei University College of Medicine, and Eyereum Eye Clinic (Kang), Seoul, South Korea; the Department of Ophthalmology & Visual Science and Department of Biomedical Engineering (Roberts), Ohio State University, Columbus, Ohio, USA; the Rio de Janeiro Corneal Tomography and Biomechanics Study Group (Ambrósio), Rio de Janeiro, Brazil; the School of Engineering (Elsheikh), University of Liverpool, Liverpool, United Kingdom

DOI
http://dx.doi.org/10.1016/j.jcrs.2017.04.036

JCRS, July 2017 Vol 43 Issue 7.


Comparison of Outcomes Between Combined Transepithelial Photorefractive Keratectomy With and Without Accelerated Corneal Collagen Cross-Linking: A 1-Year Study

Lee, Hun MD*,†; Yong Kang, David Sung MD‡; Ha, Byoung Jin MD‡; Choi, Jin Young MD‡; Kim, Eung Kweon MD, PhD†,§; Seo, Kyoung Yul MD, PhD†; Kim, Tae-im MD, PhD†,§

Journal
Cornea: October 2017 - Volume 36 - Issue 10 - p 1213–1220
doi
10.1097/ICO.0000000000001308
Category
Clinical Science

Oct 2017, Vol 36 Issue 10.

 올레이저 라섹 후 콜라겐교차결합술을 추가로 시행하는

엑스트라 수술은 각막을 재강화하고, 각막강성도)을

수술 전 수준에 가깝게 유지하며, 라섹 초기 시력안정화도 빠릅니다.


각막 내구성을 측정하는 각막강성도는

원추각막과 같은 부작용 발생의 잠재적 가능성을 확인할 있는

중요한 지표입니다. 


이번 중국 상하이 굴절교정심포지엄엔 강성용 원장을 포함해

유럽에서 처음 스마일라식을 시행한 세계적 권위자인 영국의 Walter Sekundo 교수

싱가포르 국립안과학회의 Lim Li 교수, 단 3명만이 초청연사로 참석했습니다.


-강성용 원장과 Walter Sekundo 교수-

아이리움안과는 원추각막 치료와 라식, 라섹, 스마일라식과 같은 레이저 각막굴절교정술의 

장기적 안정성을 높이는 해결책으로 각막콜라겐교차결합술에 대한 활발한 연구를 진행하고 있습니다.

그리고 과학적으로 검증받은 아이리움안과만의 수술 노하우를 국제 학회나 해외 초청 강연을 통해 전수하며

아시아 안과 수술의 안전성 향상에 기여하고 있습니다.


시력교정술, 부작용 치료의 세계적 기준!

아이리움안과는 앞으로도 시력교정술의 발전과 혁신을 위해

최선을 다하겠습니다.


대한민국소비자대상 2017 올해의 최고 브랜드 수상

아이리움안과

올해의 최고브랜드 대상 2017 Top Brand of the Year 2017


아시아 최초, 아시아 유일

avedro The World Leader in Corneal Cross-Linking Science

This is to Certify that Medical Advisory Board David Sung Yong Kang, MD EYEREUM Ophthalmic Clinic, Korea

is a member of Medical Advisory Board working with the Avedro team to develop new applications for corneal cross-linking.

November 3, 2014 David Muller, PhD President, CEO

Avedro Ambassador David Sung Yong Kang, MD