[논문] 렌즈삽입술 논문, SCI 학술지 BMC 등재
안내렌즈삽입술 안전성 향상을 위한 아이리움안과의 연구논문이
SCI 학술지 BMC에 등재됐습니다.
Lee et al. BMC Ophthalmology (2018) 18:163
https://doi.org/10.1186/s12886-018-0835-x Hun Lee 1,2, David Sung Yong Kang 3, Jin Young Choi 3, Byoung Jin Ha 3, Eung Kweon Kim 2,4, Kyoung Yul Seo 2 and Tae-im Kim 2* Background: To evaluate clinical factors affecting postoperative vaulting in eyes that had achieved optimal vaulting within the range of 250–750 μm following implantation of 12.6-mm V4c implantable collamer lenses (ICL). Methods: A total of 236 eyes of 236 patients that had achieved optimal vaulting following implantation of a 12.6-mm V4c ICL were retrospectively analyzed. Associations between postoperative vaulting and age, preoperative anterior chamber depth (ACD), preoperative axial length (AL), preoperative white-to-white diameter, preoperative pupil size, preoperative sulcus-to-sulcus diameter, and preoperative manifest refraction spherical equivalent were investigated using simple regression, stepwise multiple regression, and multinomial logistic regression analyses. Results: Mean central vaulting at the 6-month follow-up was 519.0 ± 112.8 μm. Variables relevant to postoperative vaulting were, in order of influence, preoperative ACD (β = 0.305, p < 0.001), preoperative pupil size (β = 0.218, p < 0.001), and preoperative AL (β = 0.171, p = 0.006). Low preoperative pupil size was associated with low optimal vaulting (250 to 450 μm), relative to that observed in the mid optimal vaulting group (451 to 550 μm) (odds ratio = 0.532, P = 0.021). Increasing preoperative ACD was associated with high optimal vaulting (551 and 750 μm), relative to that observed the mid optimal vaulting group (odds ratio = 6.340, P = 0.034). Conclusions: Myopic eyes with greater preoperative ACD, larger pupil size, and longer AL are predisposed to higher postoperative vaulting following 12.6-mm V4c ICL implantation. Therefore, the extremes of these parameters should be considered when choosing V4c ICL size. Keywords: 12.6-mm V4c implantable collamer lenses, Postoperative vaulting, Preoperative pupil size, Anterior chamber depth, Axial length
BMC Ophthalmology
RESEARCH ARTICLE Open Access
Analysis of pre-operative factors affecting range of optimal vaulting after implantation of 12.6-mm V4c implantable collamer lens in myopic eyes
Abstract
이보플러스 아쿠아 ICL 렌즈삽입술에서개인의 눈 조건에
적합한 렌즈사이즈 선택은 안전성과 직결됩니다.
아이리움안과 의료팀의 SCI 연구논문에 따르면
전방깊이와 동공크기가 더 클수록, 안축장이 더 길수록
렌즈와 수정체 사이의 거리인 볼팅(Vaulting)이
높아지는 경향이 나타났습니다.
따라서 안전한 렌즈삽입술을 위해서는 위와 같은
다양한 변수를 모두 고려해 개인에게 알맞은
ICL 렌즈사이즈를 결정하는 것이 중요합니다.
Lee et al. BMC Ophthalmology (2018) 18:163 Page 4 of 6 Variables in the table are ordered according to the strength of the contribution, which was based on the standardized partial regression coefficient (β)
ACD anterior chamber depth, AL axial length
Table 3 Results of stepwise multiple regression analysis to select variables relevant to central vaulting in 12.6-mm V4c implantable collamer lens implanted eyes with postoperative optimal range of vaulting
Variables Partial regression coefficient (B) Standardized partial regression coefficient (β) P R² < 0.001 0.144 Preoperative ACD (mm) 0.171 0.305 < 0.001 Preoperative pupil size (mm) 0.038 0.218 < 0.001 Preoperative AL (mm) 0.017 0.171 0.006 Constant -0.784
Low optimal vaulting, 250 to 450 μm; mid optimal vaulting, 451 to 550; high optimal vaulting, 551 and 750 μm. ACD = anterior chamber depth. Error bars represent range
Fig. 1 Subgroup analyses according to degree of postoperative vaulting.
Preoperative pupil size (mm) by Vaulting Subgroup
Subgroup Preoperative pupil size (mm) Mean/Range P-value Comparison Low optimal vaulting ~7.0 (Range ~4.7 to ~8.4) Mid optimal vaulting ~7.3 (Range ~5.0 to ~8.4) P = 0.031 (vs Low) High optimal vaulting ~7.4 (Range ~6.4 to ~8.6) P = 0.002 (vs Low) Preoperative ACD (mm) by Vaulting Subgroup
Subgroup Preoperative ACD (mm) Mean/Range P-value Comparison Low optimal vaulting ~3.3 (Range ~2.9 to ~3.9) Mid optimal vaulting ~3.4 (Range ~3.0 to ~3.8) High optimal vaulting ~3.5 (Range ~3.1 to ~3.9) P = 0.010 (vs Low)
아이리움안과 의료진은 2011년 학계 최초로
‘한국인의 눈에 맞는 ICL 렌즈사이즈 계산법’을
발표한 이래
ICL 렌즈의 생체 움직임을 규명한
다이나믹 볼팅(Dynamic Vaulting)
토릭렌즈의 회전 우려를 낮출 방안을 제시한
'난시교정 렌즈삽입술 회전 안전성' 등
뛰어난 연구성과로 렌즈삽입술의
글로벌 안전기준을 확립해왔습니다.
앞으로도 아이리움안과는
시력교정술의 안전성과
시력의 질 향상을 위한
연구와 학술 활동을
활발히 이어나가겠습니다.
